Thursday, 2 November 2017

Types

Type I: 

  • Slight spinal curvature
  • blue sclera
  • Poor muscle tone
  • loose joints
  • dentinogenesis imperfecta


TypeII:       

  • Most cases die within the first year of life due to respiratory failure or intracerebral hemorrhage
  • Severe respiratory problems due to underdeveloped lungs
  • Severe bone deformity and small stature


Type III:   


  • Short stature, spinal curvature and sometimes barrel-shaped rib cage
  • Triangular face
  • Loose joints (double jointed)
  • Discolouration of the sclera (the 'whites' of the eyes are blue)


Type IV:
  • Bones fracture easily, especially before puberty
  • Short stature, spinal curvature, and barrel-shaped rib cage
  • Bone deformity is mild to moderate
  • Early loss of hearing

Type V:It is distinguished by "mesh-like" bone appearance.

Type VI:With the same clinical features as Type IV, it is distinguished histologically by "fish-scale" bone appearance.


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